FURTHER EXPERIMENTAL STUDIES IN TETANY

Further Experimental Studies in Tetany

It has been our aim to determine in what particular the blood is altered during tetany so that it can produce hyperexcitability of the motor nerves. As a working hypothesis it has been assumed that (1) there may be a lack of calcium in the blood and tissues; (2) there may be a circulating poison which like an oxalate could render inactive the circulating calcium; and (3) there may be a substanc...

Ii. Studies in Experimental Tetany

Further Studies in Experimental Atherosclerosis

Cholesterol dissolved in sesame oil and injected regularly for a period of from 7 to 8 months into the jugular vein of four young dogs has caused in each animal larger and smaller nodules protruding to some degree into the lumen of the pulmonary artery and also here and there some diffuse thickenings, the whole closely resembling human arteriosclerosis. These changes commence at the origin of t...

Further Studies on Immunity in Experimental Cryptococcosis

Following infection with 10(3) cells of Cryptococcus neoformans, progressive multiplication occurred in all tissues for 7 to 28 days. Thereafter, most mice gained control of the infection so that 3 to 6 months after inoculation, tissues were usually sterile or contained only small numbers of cryptococci. Survivors challenged 1 to 4 months after infection with 10(3) cells lived longer than contr...

Further studies with antifoaming agents in experimental pulmonary edema.

The effect of several antifoaming agents by inhalation in preventing paroxysmal pulmonary edema was tested in a series of rabbits. Three single agents (silicone aerosol, freon, and ethyl alcohol vapor) proved beneficial; their combination did not enhance the beneficial effect. A new agent (silicone aerosol) and a new combination (10 per cent ether in alcohol by aerosol) are now ready for clinic...